Systemic infections involve the whole body (fever, malaise, organ involvement) and may be bacterial, viral, fungal, or parasitic.
Conventional medicine is essential for life-threatening systemic infections (antibiotics, antivirals, antifungals, IV fluids, hospitalization).
Homeopathy can be used in a Main role — it will help in:-
A. Reducing fever, pain, and weakness.
B. Enhancing recovery after infection.
C. Supporting immunity.
D. Preventing relapse in chronic/recurrent infections.
Some of the most common diseases are

HIV/AIDS

Sepsis

Malaria

Dengue fever

COVID-19

Rheumatic heart disease

Peripheral vascular disease